学校主页 设为首页 加入收藏 联系我们

当前位置: 学院首页 师资队伍 师资介绍 正文

周静

作者:时间:2021-03-12点击数:

周静:博士,副教授,硕士生导师

联系方式:102792@cqmu.edu.cn

主要研究方向:新型手性催化剂的设计合成、不对称催化反应、手性药物和生理活性化合物的高效高选择性合成研究。

教育与工作经历

2010-2015年,中国科学院研究生院,有机化学,硕博连读

2015-2019年,重庆医科大学,药学院,讲师

2019年至今,重庆医科大学,药学院,副教授

科研工作

作为课题负责人主持重庆市科委项目1项,重庆市教委项目1项,渝中区科委项目1项,重庆医科大学优秀青年学者项目1项,参与多项国家自然科学基金,以第一作者或通讯作者在Chem. Commun, Org. Biomol. Chem.,Tetrahedron等国际期刊上发表SCI论文十余篇。

教学工作

主要承担本科生《药物化学》、《有机化学》、《医用化学》等课程的教学工作,以通讯作者发表教改论文2篇。

代表性论文

1.JingZhou, LijuanBai, GuojuanLiang,QiguiXu,Liping Zhou,HuiZhou*. Organocatalytic asymmetric cascade 1,6-addition/hemiketalization/retro-Henry reaction of ortho-hydroxyphenyl-substitutedp-QMs with α-nitroketones.Org. Biomol. Chem.,2020,18, 2641-2645.

2.MingmingHuo#,JingZhou#, LijuanBai, QiguiXu, ZhihongZhou, HuiZhou,GuojuanLiang*. High diastereoselective synthesis of spiro-barbituratechromans via domino oxa-Michael/1,6-additionreactions of ortho-hydroxyphenylsubstituted para-quinone methides with barbiturate-based olefins.Tetrahedron2019,75, 130752.

3.Zaijun Ye, Lijuan Bai, Yan Bai, Zongjie Gan, Hui Zhou, Tao Pan, Yu Yu*,Jing Zhou*. High diastereoselective synthesis of spiro-isoxazolonechromans via domino oxa-Michael/1,6-addition reactions of orthohydroxyphenylsubstituted para-quinone methides with unsaturated isoxazolones.Tetrahedron,2019,75,682-687.

4.Jing Zhou, Guojuan Liang, Xiangnan Hu, Liping Zhou, Hui Zhou*. Facile synthesisof 3-aryl 2,3-dihydrobenzofurans via novel domino 1,6-addition/O-alkylation reactions of para-quinone methides.Tetrahedron,2018,74, 1492-1496.

5.Jing Zhou, Lijuan Bai, Guojuan Liang, Yongjie Chen, Zongjie Gan, Wu Wang, Hui Zhou and Yu Yu*. Organocatalytic asymmetric domino Michael/O-alkylation reaction for the construction of succinimide substitubstituted 3(2H)-furanones catalyzed by quinine.RSC Advances,2017,7, 39885-39888.

6.Wu Wang, Guojuan Liang, Yan Bai, Lijuan Bai, Hui Zhou, Yu Yu, andJing Zhou*. A facile base-promoted domino Michael/O-alkylation reaction for the construction of succinimide-substituted 3(2H)-furanones.Arkivoc2017, part iv, 236-248.

7.Yanshuo Zhu,Jing Zhou, Shaojing Jin, Huahui Dong, Jiaomei Guo, Xuguan Bai, Qilin Wang* and Zhanwei Bu*. Metal-free diastereoselective construction of bridged ketal spirooxindoles via a Michael addition-inspired sequence.Chem. Commun.,2017,53, 11201.

8.Shixiong Zhang#, Ping Deng#,Jing Zhou, Mouxiong Liu, Guojuan Liang, Yan Xiong and Hui Zhou. A novel homobimetallic nickel complex for the asymmetric direct Mannich reaction of imines: a practical method on a multi-gram scale.Chem. Commun.,2017,53, 12914-12917.

9.Lijuan Bai, Yuhan Chen, Yan Bai, Yongjie Chen,Jing Zhou, Ailong Huang*. Fullerene-doped polyaniline as new redox nanoprobe and catalyst in electrochemical aptasensor for ultrasensitive detection of Mycobacterium tuberculosis MPT64 antigen in human serum.Biomaterials,2017,133, 11-19.

10.Yongjie Chen, Xiaohe Luo, Lijuan Bai, Xuelian Hu,Jing Zhou, Pu Zhang and Yu Yu*. Ruthenium(II) arene complexes showing DNA photobinding: the role of the basicity of the monodentate ligand.New J. Chem.,2017,41, 10225-10230.

11.Qi-Lin Wang, Tian Cai,Jing Zhou, Fang Tian, Xiao-Ying Xu *, Li-Xin Wang*. An Unprecedented Base-Promoted Domino Reaction of Methyleneindolinones and N-Tosyloxycarbamates for the Construction of Bispirooxindoles and SpiroaziridineOxindole.Chem. Commun.,2015,51, 10726-10729.

12.Jing Zhou, Qi-Lin Wang, Lin Peng, Fang Tian, Xiao-Ying Xu* and Li-Xin Wang*. An organocatalytic domino Michael-alkylation reaction: highly enantioselective construction of spiro-cyclopentanoneoxindoles and tetronic acid Scaffolds.Chem. Commun.2014,50, 14601-14604.

13.Jing Zhou, Li-Na Jia, Qi-Lin Wang, Lin Peng, Fang Tian, Xiao-Ying Xu* and Li-Xin Wang*. Organocatalytic asymmetric cascade Michael/hemiketalization/retro-aldol reaction of 3-acetyl-oxindole with β,γ-unsaturated ketoesters catalyzed by bifunctional amino-squaramides.Tetrahedron.2014,70, 8665-8671.

14.Jing Zhou, Li-Na Jia, Lin Peng, Qi-Lin Wang, Fang Tian, Xiao-Ying Xu* and Li-Xin Wang*. Efficient asymmetric Michael reaction of 2-oxindole-3-carboxylate esters with maleimides catalyzed by cinchonidine.Tetrahedron,2014,70, 3478-3484.

下一篇:郑航

Copyright © 2019 All Rights Reserved

版权所有 © 重庆医科大学药学院 / 地址:重庆市渝中区医学院路1号 / 邮政编码:400016