李盼,博士,博士后,副研究员,硕士生导师
邮箱:lipan2019@cqmu.edu.cn;a_pan_18@126.com
主要研究方向:
(1)天然产物防治代谢性疾病的药理作用及分子机制研究;
(2)化学生物学、药物体内代谢、药物代谢动力学等相关研究;
工作经历:
2023.01-至今 重庆医科大学药学院副研究员
2020.07-2022.12重庆医科大学药学院博士后
科研项目:
(1)中国博士后科学基金会,面上资助项目(68批),2020M683270,2021-01至2022-12,8万,已结题,主持
(2)国家自然科学基金委员会,青年科学基金项目,82104469,2022-01至2024-12,30万,在研,主持
(3)重庆市教育委员会,科学技术研究项目(青年项目),KJQN202100417,4万,2021-10至2024-09,4万,在研,主持
(4)重庆市科技局,重庆市自然科学基金博士后项目,cstc2021jcyj-bsh0077,10万,2021.10-2023.09,在研,主持
代表性论文:
(1)Pan Li, Yuwei Chen, Xiumei Ke, Ruoyu Zhang, Ling Zuo, Meng Wang, Zhiwei Chen, Jianwei Wang*. Baicalin ameliorates alcohol-induced hepatic steatosis by suppressing SREBP1c elicitedPNPLA3 competitive binding to ATGL. Archives of Biochemistry and Biophysics, 2022 Jun15;722:109236
(2)Pan Li*, Ruoyu Zhang*, Meng Wang, Yuwei Chen, Zhiwei Chen, Xiumei Ke, ling Zuo, Jianwei Wang* Baicalein prevents fructose-induced Non-Alcoholic Fatty Liver Disease in rats: in regulationof fatty acid de novo synthesis, fatty acid elongation and fatty acid oxidation. Frontiers inPharmacology, 2022, 13:917329
(3)Pan Li; Liqin Ding; Shijie Cao; Xinchi Feng; Qiang Zhang; Yuwei Chen; Nan Zhang; Feng Qiu*. Curcumin metabolites contribute to the effect of curcumin on ameliorating insulin sensitivity in high-glucose-induced insulin-resistant HepG2 cells[J]. Journal of Ethnopharmacology, 2020, 259:113015.
(4) Qian Yuchen#;Li Pan#; Lv Bin; Jiang Xiaoqing; Wang Ting; Zhang Han; Wang Xiaoying*; Gao Xiumei; Heart function and thoracic aorta gene expression profiling studies of ginseng combined with different herbal medicines in enos knockout mice, Scientific Reports, 2017,7(1): 15431.(Co-first author)
(5)Li Pan#; Lv Bin#; Jiang Xiaoqing; Wang Ting; Ma Xianghui; Chang Nianwei; Wang Xiaoying*; Gao Xiumei; Identification of Nf-κb inhibitors following shenfu injection and bioactivity-integrated uplc/q-tof-ms and screening for related anti-inflammatory targets in vitro and in silico, Journal of Ethnopharmacology, 2016,194: 658-667.