基本情况

姓名：张相军

特聘副教授，副研究员，硕士生导师

任职院系：重庆医科大学药学院药剂学系

联系方式：xiangjunzhang89@sina.cn；xiangjunzhang@cqmu.edu.cn

教育经历

2016.08-2020.12 澳门大学，博士，生物医药专业

2013.09-2016.06 陆军军医大学（原第三军医大学），硕士，药剂学专业

2007.09-2011.06 山东中医药大学，学士，中草药栽培与鉴定专业

科研工作经历

2021.03-至今重庆医科大学药学院，特聘副教授

2012.05-2012.10 济南康和医药科技有限公司，药物制剂研发部

2011.04-2012.04 济南百诺医药科技开发有限公司，药物制剂研发部

参与教学工作

1）本科生《药用辅料学》、《药学导论》、《药用高分子材料学》、《生物药剂学与药物动力学》的理论课程。

2）研究生《药学前沿》的理论课程

科学研究方向

1）基于超分子大环化合物的药剂学应用

2）基于特定生理过程的纳米药物递送系统研发

3）新型纳米药物递送系统

科研课题

近年来，先后主持和参与国家自然科学基金等课题多项。

1）国家自然科学基金，青年项目，82102195，2022.01 - 2024.12，经费30万元，在研，主持。

2）重庆市自然科学基金，面上项目，CSTB2022NSCQ-MSX1073，2022.08 - 2025.07，经费10万元，在研，主持。

3）重庆市教委科学技术研究计划，青年项目，KJQN202100454,2021.10 - 2024.09，经费4万元，在研，主持。

4）国家自然科学基金，面上项目，21871301，2019.01-2022.12，经费65万元，已结题，参加。

5）澳门科技发展基金，一般科研项目，FDCT 030/2017/A1，2017.01-2019.12，经费179.5万澳门元，已结题，参加。

社会服务与任职

1）《Chinese Chemical Letters》(中国化学快报，IF:8.455)第四届青年编委（2022.1-2025.6）

2）《Chinese Medicine》《FrontiersinPharmacology》《International Journal of Pharmaceutics》审稿人

3）中国抗癌协会纳米肿瘤学专业委员会会员

发表论文

近年来，目前在Materials Today, Nano letters, Theranostics，Journal of Agricultural and Food Chemistry等领域内主流期刊以第一作者或共同第一作者身份发表学术论文8篇及参与发表论著多篇。

1. Xiangjun Zhang, Xiaoqiu Xu, Yidan Chen, Yin Dou, Xing Zhou, Lanlan Li, Chenwen Li, Huijie An, Hui Tao, Houyuan Hu, Xiaohui Li and Jianxiang Zhang, Bioinspired yeast microcapsules loaded with self-assembled nanotherapies for targeted treatment of cardiovascular disease.Materials Today, 2017,20(6): 301-313.(IF:26.416)材料科学1区

2. Xing Zhou,Xiangjun Zhang (co-first author), Songling Han, Yin Dou, Mengyu Liu, Lin Zhang, Jiawei Guo, Qing Shi, Genghao Gong, Ruibing Wang, Jiang Hu, Xiaohui Li, and Jianxiang Zhang, A yeast microcapsule-mediated targeted delivery of diverse nanoparticles for imaging and therapy via the oral route.Nano Letters, 2017, 17(2),1056-1064.(IF:11.238)材料科学1区

3. Xiangjun Zhang, Qian Cheng, Lanlan Li, Liqing Shangguan, Chenwen Li, Shengke Li, Feihe Huang, Jianxiang Zhang and Ruibing Wang, Supramolecular therapeutics to treat the side effects induced by a depolarizing neuromuscular blocking agent.Theranostics, 2019, 9(11):3107-3121.(IF:8.579)医学1区

4. Xiangjun Zhang, Xiaoqiu Xu, Shengke Li, Lanlan Li, Jianxiang Zhang and Ruibing Wang, A Synthetic Receptor as a Specific Antidote for Paraquat Poisoning.Theranostics, 2019, 9(3):633-645.(IF:8.579)医学1区

5. Hang Yin,Xiangjun Zhang (co-first author), Jianwen Wei, Siyu Lu, David Bardelang and Ruibing Wang, Recent advances in supramolecular antidotes.Theranostics,2021, 11(3):1513-1526.(IF:8.579)医学1区

6. Xiangjun Zhang, Qiaoxian Huang, Zhe-ze Zhao, Xiaoqiu Xu, Shengke Li, Hang Yin, Lanlan Li, Jianxiang Zhang and Ruibing Wang. An Eco- and User-Friendly Herbicide,Journal of Agricultural and Food Chemistry. 2019, 67(28), 7783-7792.(IF:4.192)农林科学1区

7. Xiangjun Zhang, Xiaoqiu Xu, Lian-Hui Wang, Jianxiang Zhang and Ruibing Wang, A systematic evaluation of the biocompatibility of cucurbit[7]uril in mice.ScientificReports, 2018,8:8819.(IF:3.998)综合性期刊3区

8.Yin Dou,Xiangjun Zhang (co-first author),Xiaoqiu Xu, Xing Zhou, Songling Han, Ruibing Wang, Min Su, Xiaohui Li and Jianxiang Zhang. Multiple noncovalent interactions mediated one-pot therapeutic assemblies for the effective treatment of atherosclerosis.Journal of Materials Chemistry B, 2015,3, 7355-7365.(IF:5.344)工程技术2区

参与发表论文：

1. Kuikun Yang, Guocan Yu, Zhiqing Yang, Ludan Yue,Xiangjun Zhang, Chen Sun, Jianwen Wei, Lang Rao, Xiaoyuan Chen, Ruibing Wang，Supramolecular Polymerization-Induced Nanoassemblies for Self-Augmented Cascade Chemotherapy and Chemodynamic Therapy of Tumor，Angewandte Chemie International Edition. 2021, 60, 17570-17578.(IF:15.336)化学1区

2. Kuikun Yang, Ludan Yue, Guocan Yu, Lang Rao, Rui Tian, Jianwen Wei, Zhiqing Yang, Chen Sun,Xiangjun Zhang, Mengze Xu, Zhen Yuan, Xiaoyuan Chen, and Ruibing Wang, A hypoxia responsive nanoassembly for tumor specific oxygenation and enhanced sonodynamic therapy.Biomaterials,2021,275,120822.(IF:12.479)工程技术1区

3. Jia Quan,Xiangjun Zhang, Yuanfu Ding, Shengke Li, Yang Qiu, Ruibing Wang and Xi Zhou, Cucurbit[7]uril as a Broad-Spectrum Antiviral Agent against Diverse RNA Viruses,Virologica Sinica, (2021). https://doi.org/10.1007/s12250-021-00404-9(IF:4.327)医学2区

4. Xing Zhou, Kaijian Ling, Mengyu Liu,Xiangjun Zhang, Jun Ding, Yan Dong, Zhiqing Liang, Jianjun Li and Jianxiang Zhang, Targeted Delivery of Cisplatin-Derived Nanoprecursors via a Biomimetic Yeast Microcapsule for Tumor Therapy by the Oral Route.Theranostics, 2019, 9(22):6568-6586.(IF:8.579)医学1区

5. Chenwen Li, Yang Zhao, Juan Cheng, Jiawei Guo, Qixiong Zhang, Xiangjun Zhang, Jiong Ren, Fengchao Wang, Jun Huang, Houyuan Hu, Ruibing Wang and Jianxiang Zhang, A Proresolving Peptide Nanotherapy for Site‐Specific Treatment of Inflammatory Bowel Disease by Regulating Proinflammatory Microenvironment and Gut Microbiota.Advanced Science, 2019,6(18):1900610(IF:15.840)材料科学1区

6. QiaoXian Huang, Qian Cheng,Xiangjun Zhang, Hang Yin, Lian-Hui Wang and Ruibing Wang, Alleviation of Polycation-Induced Blood Coagulation by the Formation of Polypseudorotaxanes with Macrocyclic Cucurbit[7]uril.ACS Applied Bio Materials, 2018, 1(3):544-548.化学2区

7. Chen Sun, Haipeng Zhang, Shengke Li,Xiangjun Zhang, Qian Cheng, Yuanfu Ding, Lian-Hui Wang and Ruibing Wang, Polymeric Nanomedicine with “Lego” Surface Allowing Modular Functionalization and Drug Encapsulation.ACS Applied Materials & Interfaces, 2018,10(30): 25090-25098.(IF:8.758)材料科学1区

8. QiaoXian Huang, Kit leng Kuok,Xiangjun Zhang, Ludan Yue, Simon M. Y. Lee, Jianxiang Zhang and Ruibing Wang, Inhibition of drug-induced seizure development in both zebrafish and mouse models by a synthetic nanoreceptor.Nanoscale, 2018, 10(22): 10333-10336. (IF:6.895)材料科学2区

9. Yin Dou, Yue Chen,Xiangjun Zhang, Xiaoqiu Xu, Yidan Chen, Jiawei Guo, Dinglin Zhang, Ruibing Wang, Xiaohui Li and Jianxiang Zhang, Non-proinflammatory and responsive nanoplatforms for targeted treatment of atherosclerosis.Biomaterials, 2017, 143:93-108.(IF:10.317)工程技术1区

10. Juan Cheng, Shibin Feng, Songling Han,Xiangjun Zhang, Yidan Chen, Xing Zhou, Ruibing Wang, Xiaohui Li, Houyuan Hu, and Jianxiang Zhang, Facile assembly of cost-Effective and locally applicable or injectable nanohemostats for hemorrhage control.ACS Nano, 2016, 10, 9957.(IF:14.588)材料科学1区

11. Qing Shi, Lin Zhang, Mengyu Liu, Xuelin Zhang,Xiangjun Zhang, Xiaoqiu Xu, Sha Chen, Xiaohui Li and Jianxiang Zhang,Reversion of multidrug resistance by a pH-responsive cyclodextrin-derived nanomedicine in drug resistant cancer cells.Biomaterials, 2015, 67: 169-182.(IF:10.317)工程技术1区

12. Dinglin Zhang, Yanling Wei, Kai Chen,Xiangjun Zhang, Xiaoqiu Xu, Qing Shi, Songling Han, Xin Chen, Hao Gong, Xiaohui Li and Jianxiang Zhang. Biocompatible Reactive Oxygen Species (ROS) ‐Responsive Nanoparticles as Superior Drug Delivery Vehicles.Advanced Healthcare Materials, 2015, 4(1): 69-76.(IF:7.367)工程技术2区