何丹，女，博士，副教授，硕士生导师，执业药师，重庆药学会药剂专业委员会主任委员。重庆医科大学药学院药物分析学系教师，主要从事中药质量评价和药效物质基础研究。负责/主研多项课题，包括国家科技支撑计划子课题1项，省部级科学技术项目4项，重庆市人力资源和社会保障局项目1项和多项横向项目；发表SCI收录论文35篇，CSCD核心及中文核心期刊收录论文40余篇；获国家发明专利9项；获省部级自然科学奖三等奖一项，获美国药学会优秀论文奖。副主编专著1部，参编国家规划教材5部；参与制药企业标准评审8项；西北药学杂志青年编委，Phytomedicine，Talanta, Journal of Food Measurement and Characterization等杂志审稿专家。

科研论文：

[1]Lin Yang_,Lei Dai,Weihan Qin,Yiwu Wang, Jianing Zhao, Shuxiang Pan,Dan He*. Geographical discrimination of Quisqualis indica L by UPLC-Q-TOF-MS based on qualitative and quantitative analysis combined with chemometrics.frontier in plant science，2024,https://doi.org/10.3389/fpls.2024.1418480

[2]Jingxin Xu,Mingjun Wu,Jie Yang,Dezhang Zhao,Dan He,Yingju Liu,Xiong Yan,Yuying Liu,Daojun Pu,Qunyou Tan,Ling Zhang,Jingqing Zhang.Multimodal smart systems reprogram macrophages and remove urate to treat goutyarthritis".Nature Nanotechnology,2024.07,https://doi.org/10.1038/s41565-024-01715-0

[3]Shuya Li, Ke Yin, Yiwu Wang, Lihong Tan, Jianing Zhao, Shuxiang Pan, Lin Yang,Dan He*.Integrating ICP-MS and Chemometrics for Profiling Inorganic Elements in Lianhua Qingwen Capsules and Evaluating Health Risk.Biological Trace Element Research.2024.06,DOI:10.1007/s12011-024-04279-1

[4]Lei Dai,Lin Yang, Yiwu Wang,Yan Li, Jianing Zhao, Shuxiang Pan,Yaxuan Li, Dan Yang,Dan He*.An optimized microwave digestion method to analyze the amino acids profile of Quisqualis Fructus from different origins.foods,2024,06,DOI:10.3390/foods13111645

[5]Xiaoli Xu, Lin Yang, Dezhang Zhao, Yiwu Wang, Lei Dai, Shuya Li,Dan He*.New Quality Evaluation of Qizhi Xiangfu Pills Based on Fingerprint with chemometric analysis and Quantitative Analysis of Multi-Components by Single Marker. Journal of chromatographic science. 10.1093/chromsci/bmae0052024.03

[6]Wei-han Qin, Jia-jia Zou, Lin Yang, De-zhang Zhao, Yang Yong, Lei Dai, Shu-ya Li, Yan Li,Dan He*. Study on Chemical Differences between the Seeds of Paeonia ludlowii and Oil Peony Based on UPLC-Q-TOF-MS/MS and GC-MS/MS. Journal of Food Measurement and Characterization. DOI:10.1007/s11694-024-02364-6, 2024,Feb.

[7]Lei Dai, Yang Lin, Li Yan, Shuya Li, Dan Yang, Yaxuan Li,Dan He*. Origins differentiation based on volatile constituents ofgenuine medicinal materials Quisqualis indica L via HS-GC-MS, response surface methodology and chemometric. Phytochemical Analysis. DOI：10.1002/pca.3313. 2024 Jan 8

[8]Shuya Li, Dezhang Zhao, Yuan Shen, Lei Dai, Weihan Qin, Dan Yang, Yaxuan Li, Lin Yang, Yan Li,Dan He*. Identification of Different Varieties of Oil Peony Seeds Combining ICP-MS with Chemometrics and Assessment of Associated Health Risk. Biological Trace Element Research. DOI：10.1007/s12011-023-03998-1.2023.12.

[9]LinYang, Yan Li, Yuanfang Hou, Yongfu Wu, Lihong Tan, Zhenqiang Mu, Zhaojing Zhu andDan He*. Multi-Component Analysis of Liuwei Dihuang Pills by a Single Marker Quantification Method and Chemometric Discrimination of Fingerprints. Journal of Analytical Methods in Chemistry.https://doi.org/10.1155/2023/6648668.

[10]Jia-jia Zou^#, Lin Yang^#, Xiao-li Xu, Yan Li,Dan He^*. Method Validation and Monitoring of N-nitrosodimethylamine in Metformin Hydrochloride Products in China by GC-MS/MS.Current Pharmaceutical Analysis ,2023,10DOI:10.2174/0115734129250659230929105800

[11]Jia-Jia Zou,Xiao-Li Xu,Lin Yang,Yi-Wu Wang,Yan Li,Lei Dai,andDan He* Comprehensive Quality Evaluation of Qizhi Xiangfu Pills Based on Quantitative Analysis of Multi-Components by a Single Marker Combined with GC Fingerprints and Chemometrics. Journal of AOAC INTERNATIONAL, 2023,106(5):1414-1423

主持/参与的研究课题

[1]SX样品GC-MS代谢组检测，2023年，横向，主持。

[2]盐酸二甲双胍中N-亚硝基二甲胺的检测，横向课题，2021年，主持

[3]基于七制香附丸活性成分的一测多评和指纹图谱研究，重庆市教委，2020年

[4]抗肺癌超分子EVO/BJO靶向纳米递送系统的设计及其机制研究，重庆市留创计划创新类项目，2018年

授权专利：

[1]张景勍，谭群友，何丹，柳珊。吴茱萸碱纳米乳，国家发明专利，专利号：ZL201210041981.5

[2]张景勍，罗文，何丹，赵春景。溴新斯的明多囊脂质体及其制备方法，国家发明专利，专利号：2013101331083

[3]张景勍，何丹，杨林。一种同时测定半夏提取物中尿苷、鸟苷和腺苷含量的超高效液相色谱方法.专利号：ZL 201310013570.X

[4]何丹，张景勍，孙全，杨林。一种同时测定半夏中6种有机酸含量的HPLC方法。国家发明专利，专利号ZL2015100447503