何丹，女，博士，副教授，硕士生导师，执业药师，重庆药学会药剂专业委员会委员。

主要从事中药质量评价和药效物质基础研究。负责/主研多项课题，包括国家科技支撑计划子课题1项，省部级科学技术项目4项，重庆市人力资源和社会保障局项目1项和多项横向项目；发表SCI收录论文35篇，CSCD核心及中文核心期刊收录论文40余篇；获国家发明专利9项；获省部级自然科学奖三等奖一项，获美国药学会优秀论文奖。副主编专著1部，参编国家规划教材5部；西北药学杂志青年编委，Phytomedicine，Journal of Food Measurement and Characterization等杂志审稿专家。

科研论文：

[1]Shuya Li, Ke Yin, Yiwu Wang, Lihong Tan, Jianing Zhao, Shuxiang Pan, Lin Yang,Dan He^*.Integrating ICP-MS and Chemometrics for Profiling Inorganic Elements in Lianhua Qingwen Capsules and Evaluating Health Risk.Biological Trace Element Research.2024.06,DOI:10.1007/s12011-024-04279-1

[2]Lei Dai,Lin Yang, Yiwu Wang,Yan Li, Jianing Zhao, Shuxiang Pan, Yaxuan Li, Dan Yang,Dan He*.An optimized microwave digestion method to analyze the amino acids profile of Quisqualis Fructus from different origins.foods,2024,06,DOI:10.3390/foods13111645

[3]Lei Dai,Lin Yang,Weihan Qin,Yiwu Wang, Jianing Zhao, Shuxiang Pan,Dan He^*. Geographical discrimination of Quisqualis indica L by UPLC-Q-TOF-MS based on qualitative and quantitative analysis combined with chemometrics.frontier in plant science.2024.07.https://doi.org/10.3389/fpls.2024.1418480

[4]Xiaoli Xu, Lin Yang, Dezhang Zhao, Yiwu Wang, Lei Dai, Shuya Li, Dan He^*.New Quality Evaluation of Qizhi Xiangfu Pills Based on Fingerprint with chemometric analysis and Quantitative Analysis of Multi-Components by Single Marker. Journal of chromatographic science.2024.03.DOI:10.1093/chromsci/bmae005

[5]Wei-han Qin, Jia-jia Zou, Lin Yang, De-zhang Zhao, Yang Yong, Lei Dai, Shu-ya Li, Yan Li, Dan He*. Study on Chemical Differences between the Seeds of Paeonia ludlowii and Oil Peony Based on UPLC-Q-TOF-MS/MS and GC-MS/MS. Journal of Food Measurement and Characterization. 2024,02.DOI:10.1007/s11694-024-02364-6

[6]Lei Dai, Yang Lin, Li Yan, Shuya Li, Dan Yang, Yaxuan Li, Dan He*. Origins differentiation based on volatile constituents ofgenuine medicinal materials Quisqualis indica L via HS-GC-MS, response surface methodology and chemometric. Phytochemical Analysis. 2024 Jan.DOI:10.1002/pca.3313.

[7]Shuya Li, Dezhang Zhao, Yuan Shen, Lei Dai, Weihan Qin, Dan Yang, Yaxuan Li, Lin Yang, Yan Li, Dan He*. Identification of Different Varieties of Oil Peony Seeds Combining ICP-MS with Chemometrics and Assessment of Associated Health Risk. Biological Trace Element Research. 2023.12.DOI：10.1007/s12011-023-03998-1.

[8]LinYang, Yan Li, Yuanfang Hou, Yongfu Wu, Lihong Tan, Zhenqiang Mu, Zhaojing Zhu and Dan He*. Multi-Component Analysis of Liuwei Dihuang Pills by a Single Marker Quantification Method and Chemometric Discrimination of Fingerprints. Journal of Analytical Methods in Chemistry. https://doi.org/10.1155/2023/6648668.

[9]Jia-Jia Zou,Xiao-Li Xu,Lin Yang,Yi-Wu Wang,Yan Li,Lei Dai,and Dan He* Comprehensive Quality Evaluation of Qizhi Xiangfu Pills Based on Quantitative Analysis of Multi-Components by a Single Marker Combined with GC Fingerprints and Chemometrics. Journal of AOAC INTERNATIONAL, 2023, 1–10. https://doi.org/10.1093/jaoacint/qsad043

[10]Qianqian Zhou, Yang Lin, Yiwu Wang, Jiajia Zou,Shuya Li, Lei Dai, Li Yan, Dan He*. Quality evaluation of bioactive ingredients in Lianhua Qingwen capsule based on quantitative analysis of multi-components by single marker method and chemical recognition patterns method, Journal of Chemistry,https://doi.org/10.1155/2023/2694284

[11]LinYang, Yan Li, Yuanfang Hou, Yongfu Wu, Lihong Tan, Zhenqiang Mu, Zhaojing Zhu and Dan He*. Multi-Component Analysis of Liuwei Dihuang Pills by a Single Marker Quantification Method and Chemometric Discrimination of Fingerprints.Journal of Analytical Methods in Chemistry.https://doi.org/10.1155/2023/6648668

[12]Xie J, Zhong C, Wang T, He D, Lu L, Yang J, Yuan Z, Zhang J. Better bioactivity, cerebral metabolism and pharmacokinetics of natural medicine and its advanced version. Front Pharmacol. 2022. DOI: 10.3389/fphar.2022.937075

[13]Zhang RT, Qing WW, Yang L, Zou JJ, Shi YT, Xu XL, He D*. Fingerprint combining with quantitative analysis of multi-components by single marker for quality control of Chenxiang Huaqi tablets. Phytochem Anal. 2021,33(3): 335-343

主持/参与的研究课题

[1]SX样品GC-MS代谢组检测，2.6万，2023.03-2023.06，横向，主持。

[2]盐酸二甲双胍中N-亚硝基二甲胺的检测，横向课题，8.84万，主持

[3]基于七制香附丸活性成分的一测多评和指纹图谱研究，2020年重庆市第九期雏鹰计划立项，编号：CY200412，2020.06.30至2021.06.30，2.7万，主持

[4]沉香化气片质量标准提升研究，重庆市重点产业共性关键技术创新专项子课题，2016.10.01-2019.10.01，20万，主研

[5]抗肺癌超分子EVO/BJO靶向纳米递送系统的设计及其机制研究，2018年重庆市留创计划创新类项目，编号：CX2018104，5万，2018年11月，主持

授权专利：

[1]张景勍，谭群友，何丹，柳珊。吴茱萸碱纳米乳，国家发明专利，专利号：ZL201210041981.5授权日2014-08-13

[2]张景勍，罗文，何丹，赵春景。溴新斯的明多囊脂质体及其制备方法，国家发明专利，专利号：2013101331083。2013年3月31日

[3]张景勍，何丹，杨林。一种同时测定半夏提取物中尿苷、鸟苷和腺苷含量的超高效液相色谱方法.专利号：ZL 201310013570.X。授权日公告日2016年02月03日

[4]何丹，张景勍，孙全，杨林。一种同时测定半夏中6种有机酸含量的HPLC方法。国家发明专利，专利号ZL2015100447503，授权公告日2017年1月25日。专利申请日期2015年1月27日

[5]张景勍，熊华荣，周岐新，周云莉，何丹，胡雪原。尿酸酶多囊脂质体及其制备方法。专利号：201410271072X，授权公告日：2017.03.01