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冉光尧

作者:时间:2021-10-20点击数:

冉光尧,男,特聘副教授,副研究员,硕士生导师

邮箱:460909458@qq.comgyran@cqmu.edu.cn

教育工作经历:

2020.09-至今重庆医科大学药学院药物化学系特聘副教授

2017.09-2020.08四川大学华西药学院药物化学专业博士(导师:陈应春教授)

2014.09-2017.06四川大学华西药学院药物化学专业硕士(导师:陈应春教授)

2010.09-2014.06重庆医科大学药学院药物分析专业本科

研究方向:不对称催化合成;生物活性分子合成及评价

教学:承担本科生《药物化学》、《药物设计学》课程,研究生《药物分子设计》课程。

承担研究项目

1.青年科学基金项目,2210010115,30万元,在研,主持。

2.重庆市自然科学基金(面上项目),10万元,在研,主持。

研究成果(通讯作者/第一作者):

1.Shu-Yi Wu, Yang Li, Peng Shen, Xin-Han Yang,Guang-Yao Ran.Palladium-catalysed fragmentary esterification-induced allylic alkylation of allyl carbonates and cyclic vinylogous anhydrides.Chem. Commun.2024,60, 1416–1419.(IF2024= 4.9)

2.Liu Shi, Qiang Xiong, Shu-Yi Wu, Yang Li, Peng Shen, Ji Lu,Guang-Yao Ran.Enantioselective Synthesis of Ten-Membered Lactones via Palladium-Catalyzed [5 + 5] Annulation.Org. Lett.2023,25, 2030–2035.(IF2023= 6.072)

3.Qiang Xiong, Ji Lu, Liu Shi,Guang-Yao Ran.Pd-Catalyzed Tandem [5 + 2] Cycloaddition/Ring Contraction of Phthalide-Derived Alkenes and Vinylethylene Carbonates for the Construction of Benzo-[5,5]-spiroketal Lactones.Org. Lett.2022,24, 3363–3367. (IF2022= 6.072)

4.Guang-Yao Ran, Chen Chen, Xing-Xing Yang, Zhi Zhao, Wei Du, and Ying-Chun Chen. Cu(I)-Catalyzed Asymmetric α‑Allenylation of Activated Ketimineswith 3‑Butynoates.Org. Lett.2020,22, 4732−4736. (IF2021= 6.005)

5.Guang-Yao Ran, Xing-Xing Yang, Jing-Fei Yue, Wei Du, Ying-Chun Chen. Asymmetric Allylic Alkylation with Deconjugated Carbonyl Compounds: Direct Vinylogous Umpolung Strategy.Angew. Chem. Int. Ed.2019,58, 9210-9214.(IF2021=15.336)Ø

6.Guang-Yao Ran, Ming Gong, Jing-Fei Yue, Xing-Xing Yang, Su-Lan Zhou, Wei Du, and Ying-Chun Chen. Asymmetric Cascade Assembly of 1,2-Diaza-1,3-dienes and α,β-UnsaturatedAldehydes via Dienamine Activation.Org. Lett.2017,19, 1874-1877. (IF2021= 6.005)

7.Guang-Yao Ran, Pan Wang, Wei Dua, Ying-Chun Chen. α-Regioselective [3 + 2] annulations with Morita–Baylis–Hillman carbonates of isatins and 2-nitro 1,3-enynes.Org. Chem. Front.2016,3, 861-864. (IF2021=5.281)

8.Jing Peng,Guang-Yao Ran, Wei Du, and Ying-Chun Chen. Divergent Cyclization Reactions of Morita−Baylis−Hillman Carbonates of 2-Cyclohexenone and Isatylidene Malononitriles.Org. Lett.2015,17, 4490-4493. (IF2021= 6.005)

9.Ran, Guangyao. Chen, Yingchun. Construction of Chiral 2,3-Allenols through Copper(I)-Catalyzed Asymmetric Direct Alkynylogous Aldol Reaction.Chin. J. Org. Chem.2020,40, 814-815.

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