博士,重庆医科大学药学院副教授,硕士研究生导师
电子邮箱:pfzhouchem@cqmu.edu.cn
2014年本科毕业于四川大学化学学院,随后师从冯小明教授留校继续学习,并于2019年获得博士学位。同年进入杜克大学进行博士后研究,合作导师为StevenMalcolmson教授。2023年6月以青年创新人才引进到重庆医科大学药学院工作。主要从事有机合成方法学、药物化学等方面的研究。迄今在J.Am. Chem. Soc.;Angew. Chem. Int. Ed.; ACS Catalysis等国际知名期刊发表论文近20篇。
主要研究领域:
药物及生物活性分子后期修饰
有机合成方法学开发
教育及科研工作经历:
2023/06– 重庆医科大学,药学院,特聘副教授
2019/07–2022/06杜克大学,博士后(合作导师:StevenMalcolmson)
2014/09–2019/06四川大学化学学院,理学博士(导师:冯小明院士)
2010/09–2014/06四川大学化学学院,理学学士(导师:冯小明院士)
代表性论文:
1. Pengfei Zhou, Xinxin Shao*, and Steven J. Malcolmson*, A Diastereodivergent and Enantioselective Approach to syn- and anti-Diamines: Development of 2-Azatrienes for Cu-Catalyzed Reductive Couplings with Imines That Furnish Allylic Amines,J. Am. Chem. Soc.2021,143, 13999-14008. (IF = 16.383, Highlighted by JACS spotlights).
2. Pengfei Zhou, Lili Lin, Long Chen, Xia Zhong, Xiaohua Liu, and Xiaoming Feng*, Iron-Catalyzed Asymmetric Haloazidation ofa,b-Unsaturated Ketones: Construction of Organic Azides with Two Vicinal Stereocenters,J. Am. Chem. Soc.2017,139, 13414–13419. (IF = 16.383)
3. Pengfei Zhou, Yunfei Cai, Xia Zhong, Weiwei Luo, Tengfei Kang, Jun Li, Xiaohua Liu,* Lili Lin, and Xiaoming Feng*, Catalytic Asymmetric Intra- and Intermolecular Haloetherification of Enones: An Efficient Approach to (-)-Centrolobine,ACS Catal.2016,6, 7778–7783. (IF = 13.7)
4. Pengfei Zhou, Xiaohua Liu*, Wangbin Wu, Chaoran Xu, and Xiaoming Feng*, Catalytic Asymmetric Construction of β-Azido Amides and Esters via Haloazidation,Org. Lett.2019,21, 1170–1175. (IF = 6.072)
5. Pengfei Zhou, Yunfei Cai, Lili Lin, Xiangjin Lian, Yong Xia, Xiaohua Liu, and Xiaoming Feng*, Asymmetric Synthesis of Spirocyclic Oxindole-Fused Tetrahydrothiophenes viaN,N′-Dioxide–Nickel(II) Catalyzed Domino Reaction of 1,4-Dithiane-2,5-diol with 3-Alkenyloxindoles,Adv. Synth. Catal.2015,357, 695–700. (IF = 5.981).
6.PengfeiZhou, QianYang, YongTang, YunfeiCai*,Recent trends in metal-doped carbon nitride-catalyzed heterogeneous light-driven organic transformations,Nano Trends,2023,4,100019.
获得主要奖励:
2017年博士研究生国家奖学金;唐敖庆化学奖学金
2018年博士研究生国家奖学金